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Genetic study of PD-L1 and CD8 in patients of oral squamous cell carcinoma

Expression of Programmed Death -Ligand 1 (PD-L1) and CD8 in oral squamous cell carcinoma and its association with clinicopathological parameters - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/07/070917
Enrollment
30
Registered
2024-07-19
Start date
Unknown
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C048- Malignant neoplasm of overlappingsites of floor of mouth Health Condition 2: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx Health Condition 3: C068- Malignant neoplasm of overlappingsites of other and unspecified parts of mouth

Interventions

Intervention1: NIL: NIL Control Intervention1: NIL: NIL

Sponsors

Maulana Azad Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) All the newly diagnosed cases of primary oral squamous cell carcinoma whose samples are received in the Department of Pathology,MAMC 2) Age more than 18 years

Exclusion criteria

Exclusion criteria: 1)Patients who have received radiotherapy and/or chemotherapy. 2) Patients having previous history of any other malignancy

Design outcomes

Primary

MeasureTime frame
Proportion of cases of oral squamous cell carcinoma showing PD-L1 and CD8 expressionTimepoint: Baseline—

Secondary

MeasureTime frame
Association between expression of PD-L1 and CD8 with clinicopathological parameters like age, Sex, duration of symptoms, tumor size, location, grade, stage, metastasis, lympho-vascular invasion, perineural invasion.Timepoint: Baseline—

Countries

India

Contacts

Public ContactDr Varuna Mallya

Maulana Azad Medical College

varunamallya@gmail.com9599966089

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026