To compare general anaesthesia versus spinal anaesthesia in patients undergoing bladder hydrodistension for interstitial cystitis.

A randomized prospective comparative clinical study of Hemodynamic responses during bladder hydrodistension under general versus spinal anaesthesia in patients with interstitial cystitis in department of anaesthesia, SMS Medical College, Jaipur - nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/07/070904

Enrollment

Registered

2024-07-19

Start date

Unknown

Completion date

Unknown

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N301- Interstitial cystitis (chronic) Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: General Anaesthesia: Patient will be induced 5 minutes prior the bladder hydrodistension with propofol in the dose of 2mg/kg after giving premedication which are inj. midazolam (0.05mg/

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients scheduled for elective bladder hydrodistension.2. Patients willing to give informed consent. American Society of Anaesthesiologist physical status I-III.

Exclusion criteria

Exclusion criteria: 1.Patient should not be part of any other study.2.Un-cooperative patient.3.Patient who is allergic to any drug of general or spinal anaesthesia.4.Patient who is on anticoagulants.5.Patients with raised intra cranial pressure.6.Patients with severe cardiovascular diseases.7.Patients with spinal deformity or local site infection.

Design outcomes

Primary

Measure	Time frame
To determine and compare the maximum increase in heart rate, mean arterial pressure, systolic blood pressure and diastolic blood pressure during bladder hydrodistension from baseline in general versus spinal anaesthesia.Timepoint: To determine and compare the maximum increase in heart rate, mean arterial pressure, systolic blood pressure and diastolic blood pressure at baseline, 2 minutes after induction, 5 minutes, 15 minutes, 25 minutes, 35 minutes and 45 minutes during bladder hydrodistension from baseline in general versus spinal anaesthesia.	—

Measure

Time frame

To determine and compare the maximum increase in heart rate, mean arterial pressure, systolic blood pressure and diastolic blood pressure during bladder hydrodistension from baseline in general versus spinal anaesthesia.Timepoint: To determine and compare the maximum increase in heart rate, mean arterial pressure, systolic blood pressure and diastolic blood pressure at baseline, 2 minutes after induction, 5 minutes, 15 minutes, 25 minutes, 35 minutes and 45 minutes during bladder hydrodistension from baseline in general versus spinal anaesthesia.

—

Secondary

Measure	Time frame
1.To evaluate post-operative pain using NRS pain score during their stay in post anaesthesia care unit (PACU).Timepoint: 30 minutes after completion of procedure.	—

Countries

India

Contacts

Public ContactDr Archie Sharma

Sawai Man Singh Medical College

anupamag213@gmail.com9414240245

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026