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Role of photodynamic therapy in diabetic patients with apical periodontitis.

Role Of Antimicrobial Photodynamic Therapy During Non Surgical Root Canal Treatment Of Teeth Having Apical Periodontitis In Individuals With Type 2 Diabetes Mellitus – A Clinical And Radiographic Evaluation. - nil

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/07/070900
Enrollment
42
Registered
2024-07-19
Start date
Unknown
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K045- Chronic apical periodontitis

Interventions

Intervention1: Photodynamic therapy: Root canal treatment using photodynamic therapy with nontoxic photosensitizer dye as disinfection method which will be used 3 times for 30 sec duration. Control In

Sponsors

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with a history of type 2 DM (with HbA1c =6.5%) 2. Mature permanent teeth with apical periodontitis as confirmed by a negative response to cold and electric pulp tests 3. Radiographic evidence of AP (minimum size 2 mm ×2 mm)

Exclusion criteria

Exclusion criteria: 1. Patients with Periodontitis with pocket depth = 4mm 2. Systemic disorders other than diabetes mellitus (type 2) 3. Patients taking steroids, pregnant patients 4. Patients with cracks/fractures of the tooth 5. Patients who underwent a procedural errors 6. Smokers 7. Patients with a history of antibiotic intake in the preceding month were excluded from the study.

Design outcomes

Primary

MeasureTime frame
change in apical bone density (PAI score) at 3, 6 months time interval and the presence of clinical signs & symptoms or abnormal findings (ie, spontaneous pain, presence of sinus tract, swelling, mobility, periodontal probing depth greater than baseline measurements, or sensitivity to percussion and palpation).Timepoint: Baseline, 3 & 6 months

Secondary

MeasureTime frame
Comparison of the periapical healing with glycemic level of the patientTimepoint: Baseline, 6 months

Countries

India

Contacts

Public ContactDr Pragya pandey

Faculty of Dental Sciences King Georges Medical university Lucknow

rameshbharti@kgmcindia.edu9935724723

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026