Health Condition 1: R99- Ill-defined and unknown cause of mortality
Conditions
Interventions
Intervention1: Nil: Nil
Sponsors
All India Institute of Medical sciences, Jodhpur
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients aged above 18 years 2. Patients having clinical features suggestive of sepsis as defined by Sepsis-3 definition (2016) at the time of ICU admission
Exclusion criteria
Exclusion criteria: 1. The patient/relatives who refused to give Informed consent 2. Age less than 18 years 3. Patients with terminal stage of disease (malignant cancer of any type, acquired immunodeficiency syndrome, end-stage liver or renal disease). 4. HIV/HBsAg/HCV 5. Autoimmune disorders/Metabolic diseases 6. On long term steroids/ Immunosuppressants/ Chemotherapy 7. Osteoarthritis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary objective is to compare the diagnostic accuracy of mid regional Proadrenomedullin with procalcitonin for diagnosis of sepsis in Critically Ill patients.Timepoint: Day 0 and at day 7 or day of death or discharge whichever is earlier. | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate the ability of Proadrenomedullin to prognosticate the multi organ failure in critically ill sepsis patients as assessed by SOFA scores. To establish Proadrenomedullin as a predictor of outcome of sepsis in terms of 28 days mortality. To compare Proadrenomedullin, procalcitonin values as a prognostic marker of sepsis. Timepoint: Follow up for 7 days or till date of death. | — |
Countries
India
Contacts
Public ContactDR Malarvizhi E
Department of Anaesthesiology and Critical care, AIIMS Jodhpur
Outcome results
None listed