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To observe the effects of intravenous drug amisulpride for the avoidance of postoperative nausea and vomiting after general anaesthesia.

To observe the efficacy of intravenous amisulpride for the prevention of postoperative nausea and vomiting in patients undergoing surgeries under general anaesthesia. - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/07/070858
Enrollment
50
Registered
2024-07-18
Start date
Unknown
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: O- Medical and Surgical Health Condition 3: O- Medical and Surgical

Interventions

Intervention1: Nil: Nil Control Intervention1: Nil: Nil

Sponsors

Shree Krishna Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients scheduled for surgery under general anaesthesia 2.Patients who are able to provide informed and written consent. 3.Patients with ASA status I,II,III

Exclusion criteria

Exclusion criteria: 1.Refusal to give written and informed consent. 2.Haemodynamically unstable (patients in shock or on vasopressor support). 3.Patients expected to require post-operative ventilation or need a nasogastric tube or oro-gastric tube in situ after surgery. 4.Patients with Parkinson disease or a preexisting vestibular disorder or history of dizziness, a history of alcohol abuse, a clinical significant cardiac arrhythmia or epilepsy. 5.History of drug allergy/allergy to study drugs. 6.On steroid therapy, opioid therapy or medications causing nausea/vomiting 7.Pregnant and lactating patients. 8.Patients who received antiemetic drugs within 24 h before anesthesia. 9.Patients with congenital long QT syndrome

Design outcomes

Primary

MeasureTime frame
To observe the incidence of post operative nausea and vomiting in patients undergoing elective or emergency surgery under general anaesthesiaTimepoint: Post operative period 0-24 hours

Secondary

MeasureTime frame
1.To assess Time of incidence of post operative nausea and vomiting from the administration of amisulpride. 2.To assess Frequency of rescue antiemetic(ondansetron) given after the occurrence of PONV in the 24 hours period postoperatively 3.Type of rescue analgesics given in the first 24 hours postoperative period. Timepoint: Post operative period 0-24 hours

Countries

India

Contacts

Public ContactDr Mayur Limbachiya

Pramukhswami Medical College,Shree Krishna Hospital, Bhaikaka University

mayurbapa@gmail.com9099242212

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026