Epidural labour analgesia- comparison between fentanyl and dexamethasone as adjuvant

Comparison of epidural dexamethasone-ropivacaine and fentanyl-ropivacaine for ambulatory labour analgesia- A triple blind prospective randomized study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/07/070752

Enrollment

Registered

2024-07-16

Start date

Unknown

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: O00-O9A- Pregnancy, childbirth and the puerperium

Interventions

Intervention1: Epidural labour analgesia: COMPARING EFFECT OF TWO DRUG COMBINATION FOR AMBULATORY LABOUR ANALGESIA Control Intervention1: DR(dexamethasone-ropivacaine) vs FR(fentanyl-ropivacaine): COM

Eligibility

Inclusion criteria

Inclusion criteria: Singleton pregnancy with cephalic presentation in established labor with contractions that occur at regular intervals and become stronger with passage of time (NICE guidelines). Term pregnancy with POG ranging from 37-41 weeks Reassuring cardiotocographic finding Patients requesting for ambulatory labor analgesia

Exclusion criteria

Exclusion criteria: Patient refusal for the procedure. Local infection at site of epidural catheter placement. Thrombocytopenia. Coagulopathies. HELLP syndrome. PROM Sepsis. Deafness. Spinal column deformities and spine surgery. Patient having hypersensitivity to the study drug. In case of Intrathecal catheter placement. In case of accidental dural puncture.

Design outcomes

Primary

Measure	Time frame
To compare the total amount of ropivacaine when used with dexamethasone in one group and when used with fentanyl in the other group in laboring parturients with ambulatory epidural labor analgesiaTimepoint: To check the vitals, drug consumption, ambulation at 0 minute, 15 minutes,30 minutes and then every hour	—

Secondary

Measure	Time frame
blood pressure, heart rate, respiratory rate, oxygen saturation throughout the obstetrical variables including duration of labour, mode of delivery, intrapartum & postpartum complications. duration of ambulation in both groups. perinatal outcome including live birth/still birth, APGAR score at 1 & 5 mins, & NICU admissions effect of ambulation on duration of first & second stage of labour. incidence of maternal fever in both groups upto 12 hrs . incidence of maternal hyperglycemia in both groups upto 12 hrs. patients’ satisfaction. Obstetrician satisfaction Timepoint: 0 MIN 5 MIN 15MIN EVERY 15 MIN TILL ONE HOUR EVERY 30 MIN UNTIL DELIVERY	—

Measure

Time frame

blood pressure, heart rate, respiratory rate, oxygen saturation throughout the obstetrical variables including duration of labour, mode of delivery, intrapartum & postpartum complications. duration of ambulation in both groups. perinatal outcome including live birth/still birth, APGAR score at 1 & 5 mins, & NICU admissions effect of ambulation on duration of first & second stage of labour. incidence of maternal fever in both groups upto 12 hrs . incidence of maternal hyperglycemia in both groups upto 12 hrs. patients’ satisfaction. Obstetrician satisfaction Timepoint: 0 MIN 5 MIN 15MIN EVERY 15 MIN TILL ONE HOUR EVERY 30 MIN UNTIL DELIVERY

—

Countries

India

Contacts

Public ContactDr Asma Anjum

Dr rajendra prasad government medical college, kangra at tanda

drbharti203@gmail.com9418044928

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026