Comparing the effect of ketamine-dexmedetomidine and ketamine-propofol for short surgical procedure

A comparison of ketodex and ketofol for procedural sedation- prospective randomized control study - Nil

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/07/070727

Enrollment

Registered

2024-07-16

Start date

Unknown

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Ketamine dexmedetomidine (ketodex): Total of 60 patients will be divided into two groups (30 patients in each group) by computer generated randomization. In group A (ketodex) ketamine 1

Eligibility

Inclusion criteria

Inclusion criteria: ASA I and II Short surgical procedure lasting for less than one hour BMI less than 29.9

Exclusion criteria

Exclusion criteria: ASA III or more Allergic to study drugs BMI more than 30 Anticipated difficult airway

Design outcomes

Primary

Measure	Time frame
To compare efficacy of ketodex versus ketofol combination for short surgical procedures in terms of sedation haemodynamic stability and respiratory stability to compare mean recovery between ketodex versus ketofol.Timepoint: Following administration of study drugs 0minute, 5th, 10th, after that every 15 minutes till completion of procedure. In the post operative ward till 1hour following the completion the procedure.	—

Measure

Time frame

To compare efficacy of ketodex versus ketofol combination for short surgical procedures in terms of sedation haemodynamic stability and respiratory stability to compare mean recovery between ketodex versus ketofol.Timepoint: Following administration of study drugs 0minute, 5th, 10th, after that every 15 minutes till completion of procedure. In the post operative ward till 1hour following the completion the procedure.

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Secondary

Measure	Time frame
Sedation score pre & post op after induction upto recovery, Recovery time, Time to rescue analgesic, Incidence of side effect (delirium, nausea, vomiting)Sedation score – pre & post op after induction upto recovery, Recovery time, Time to rescue analgesic, Incidence of side effect (delirium, nausea, vomiting) Timepoint: Following administration of study drugs 0minute, 5th, 10th, after that every 15 minutes till completion of procedure. In the post operative ward till 1hour following the completion the procedure.	—

Measure

Time frame

Sedation score pre & post op after induction upto recovery, Recovery time, Time to rescue analgesic, Incidence of side effect (delirium, nausea, vomiting)Sedation score – pre & post op after induction upto recovery, Recovery time, Time to rescue analgesic, Incidence of side effect (delirium, nausea, vomiting) Timepoint: Following administration of study drugs 0minute, 5th, 10th, after that every 15 minutes till completion of procedure. In the post operative ward till 1hour following the completion the procedure.

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Countries

India

Contacts

Public ContactANBUSELVI ANOUMANDANE

ACS medical college and Hospital, Chennai

dranbu11@gmail.com9677817720

Outcome results