Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Sugammadex: Sugammadex 2mg/kg administered intravenously before extubation after tof attained more than 0.9
Control Intervention1: Neostigmine: Neostigmine 50 mics/kg administered intra
Sponsors
Post Graduate Institute of Medical Education and Research
Eligibility
Inclusion criteria
Inclusion criteria: Patients undergoing elective cardiac surgery with CPB planned for on table extubation ASA classification 1-3
Exclusion criteria
Exclusion criteria: Allergic to Sugammadex or neostigmine or having any contraindications Emergency cardiac surgery Surgery under moderate to deep hypothermia Patient not giving written informed consent Patient with ejection fraction less than 30% ASA classification more than III
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The time interval from administering the reversal agent to the extubation.Timepoint: immediately | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to attain TOF more than 0.9. Residual paralysis (TOF less than 0.9) Respiratory complications (hypoxemia, hypercarbia), Reintubation within 2 hours of extubation Prolonged ICU stay duration Requirement of non-invasive ventilation in ICU.Timepoint: 48 hours | — |
Countries
India
Contacts
Public ContactSunder Lal Negi
Post Graduate Institute of Medical Education and Research Chandigarh
Outcome results
None listed