Comparison of Erector Spinae Plane block with Intrathecal Morphine for post-operative pain relief in patients undergoing surgery for gynaecological malignancies.

Comparison of Erector Spinae Plane block with Intrathecal Morphine for post-operative analgesia in patients undergoing surgery for gynaecological malignancies. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/07/070669

Enrollment

Registered

2024-07-16

Start date

Unknown

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C51-C58- Malignant neoplasms of female genital organs

Interventions

Intervention1: Erector Spinae Plane Block with Intrathecal Morphine: 20 ml of 0.25% bupivacaine each injected bilaterally at L2-L3 level in erector spinae plane block in the pre-induction period compa

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients of age 18-80 years 2. Patients fulfilling American Society of Anesthesiologists (ASA) physical status I, II, III criteria. 3. BMI: 18-35kg/m2 (body weight atleast 40 kg) 4. Surgical approach via midline abdominal incision.

Exclusion criteria

Exclusion criteria: 1. Known allergy to the drugs in the study 2. Pregnancy 3. Any contraindication to a regional/neuraxial local anesthetic, such as bleeding disorders or local infection 4. History of chronic pain or patient on chronic pain medication 5. Drug abuse

Design outcomes

Primary

Measure	Time frame
Time to request for first rescue analgesia.Timepoint: 24 hours in the post-operative period	—

Secondary

Measure	Time frame
1. Numerical Rating Scale at 2,4,6,12 and 24 hours postoperatively. 2. Total consumption of intravenous fentanyl intraoperatively. 3. Number of patients reporting any opioid related complications over 24 hours postoperatively (pruritis, nausea and vomiting) 4. Total consumption of rescue analgesic medication in 24 hours. 5. Sedation score at 2,4,6,12, and 24 hours postoperatively 6. Quality of recovery ( QoR-15 ) at 24 hours post operatively. 7. Patient satisfaction score at 24 hours postoperativelyTimepoint: 12 months	—

Measure

Time frame

1. Numerical Rating Scale at 2,4,6,12 and 24 hours postoperatively. 2. Total consumption of intravenous fentanyl intraoperatively. 3. Number of patients reporting any opioid related complications over 24 hours postoperatively (pruritis, nausea and vomiting) 4. Total consumption of rescue analgesic medication in 24 hours. 5. Sedation score at 2,4,6,12, and 24 hours postoperatively 6. Quality of recovery ( QoR-15 ) at 24 hours post operatively. 7. Patient satisfaction score at 24 hours postoperativelyTimepoint: 12 months

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Countries

India

Contacts

Public ContactAarushi Aggarwal

Maulana Azad Medical College

drrahilsingh@gmail.com981071902

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026