Health Condition 1: E66- Overweight and obesity
Conditions
Interventions
Intervention1: Alternate Day Fasting (ADF): Participants to fast on alternate days, consuming only 25% of one day calorie requirement.
A routine diet on non-fasting days.
Intervention2: The 5:2 Diet:
Sponsors
Maulana Azad Medical College and Associated Hospitals
Eligibility
Inclusion criteria
Inclusion criteria: 1. Body Mass Index equals or greater than 23 kilograms per square meter (as per WHO Asian BMI classification), 2. Able to give informed consent, 3. Not planning to relocate within 6 months of the study, 4. Willing to participate in this weight loss intervention.
Exclusion criteria
Exclusion criteria: 1. Individuals suffering from disorders like Celiac disease, uncontrolled thyroid disorder, anorexia bulimia. 2. Individuals with comorbid conditions in which dietary restrictions will be detrimental like individuals with Stroke, Cardiomyopathy, Coronary artery disease, other Cardio-vascular disease, Chronic Obstructive Pulmonary Disease, Alzheimers disease, Depression. 3. Individuals who have previous weight loss surgery, moderate or severe chronic hepatorenal diseases or cardio-cerebrovascular diseases, current acute complications of diabetes, such as diabetic ketosis, hyperglycaemia and hypertonicity in the past 3 months, stress diseases such as surgery, trauma, and cardiovascular and cerebrovascular events, and mental disorders requiring antipsychotic drugs. 4. Women who are lactating, pregnant or planning for pregnancy. 5. Individuals undergoing some weight loss intervention or have undergone weight loss intervention within 3 months tim
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in body weight, body mass indexTimepoint: At Baseline 0 week At Midline 6 weeks At Endline 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Lipid levels, Fasting Blood Glucose, HbA1C, HOMA IR, Fasting insulin, Ferritin, IL-6, Adiponectin, Total energy intake. Improvement in quality of life and parameters like physical, emotional and social well-beingTimepoint: At Baseline 0 week At Endline 12 weeks;reduction in body fat, visceral fat, improvement in waist to hip ratioTimepoint: At Baseline 0 week At Midline 6 weeks At Endline 12weeks | — |
Countries
India
Contacts
Public ContactShikha Goel
Maulana Azad Medical College and Associated Hospitals
Outcome results
None listed