Health Condition 1: - Health Condition 2: M170- Bilateral primary osteoarthritis of knee
Conditions
Interventions
Intervention1: 1.Safuf(powder)-oral
2.Roghan Gul e Aak-Topical: 1.Safuf(powder)
Dosage Form :Safuf(Powder)
Dosage:3.5gms BD after meal with water
Mode of Administration: oral
Composition Of Safuf:Sibr
Sponsors
National Research Institute of Unani Medicine for Skin Disorders
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients of any sex aged between 40to 65years 2.Clinical and Radiographic Knee Osteoarthritis as per the following American College of Rheumatology (ACR) criteria: a. Knee Pain b. Osteophytes on Knee Radiograph, and c. At least 1 of the following 3 criteria: i. Age =40 years ii. Morning Stiffness lasting =30 minutes iii. Crepitus on Active Knee Motion 3.Knee OA of Kellgren-Lawrence Grade 1 to 3 4.Participants who are able and willing to comply with the protocol and to sign IEC approved ICF
Exclusion criteria
Exclusion criteria: 1.Knee OA of Kellgren-Lawrence grade IV 2. Secondary OA, Inflammatory joint diseases (e.g. RA, psoriatic arthritis, gout), or any other type of arthritis 3.Patients on long-term steroid treatment 4.H/o having received intra-articular knee injection (corticosteroids or hyaluronan), or any investigational drug in the previous one month 5.Pregnant or Lactating Women 6.Significant Pulmonary/Cardiovascular/Hepato-renal Dysfunction 7.Known cases of Immunocompromised states (HIV/ AIDS, etc.)/ Malignancies
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Reduction in Pain by Using VAS 2.Reduction in WOMAC Scores from baselineTimepoint: 42 Days | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Joint Tenderness On a 4 Point Likert Scale 2.50 Foot Walk TestTimepoint: 42 Days | — |
Countries
India
Contacts
Public ContactAtiya Begum
National Research Institute of Unani Medicine for Skin Disorders
Outcome results
None listed