To study the comparison of two groups of participants of knee surgeries using blocks as intervention and to compare the effect on pain relief and physical activity as main outcome.

Comparison of 4 in 1 block with modified 4 in 1 block using ultrasound for postoperative analgesia in cruciate ligament reconstruction in knee surgeries. - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/07/070621

Enrollment

Registered

2024-07-15

Start date

Unknown

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M170- Bilateral primary osteoarthritis of knee

Interventions

Intervention1: 4 in 1 block: Patients in this group will receive single injection 4 in 1 block using ultrasound with 20 ml bupivacaine 0.25% and 2ml (8mg) dexamethasone as adjuvant [total -22 ml drug]

Eligibility

Inclusion criteria

Inclusion criteria: ASA I and II ,who are to undergo elective orthopaedic cruciate ligament reconstruction in knee surgery, under subarachnoid block

Exclusion criteria

Exclusion criteria: Known hypersensitivity or allergy to study drugs. Bleeding disorders. Infection at the site of the block. Uncontrolled diabetes mellitus and hypertension. History of cardiac, liver or kidney disease. Patient not willing to participate in the study.

Design outcomes

Primary

Measure	Time frame
To compare 4 in 1 block with modified 4 in 1 block using ultrasound for post-operative analgesia in cruciate ligament reconstruction in knee surgeries by comparing the difference of VAS (visual analogue scale) scores between the two groups for 48 hours after surgery.Timepoint: To compare 4 in 1 block with modified 4 in 1 block using ultrasound for post-operative analgesia in cruciate ligament reconstruction in knee surgeries by comparing the difference of VAS (visual analogue scale) scores between the two groups for 48 hours after surgery.	—

Measure

Time frame

To compare 4 in 1 block with modified 4 in 1 block using ultrasound for post-operative analgesia in cruciate ligament reconstruction in knee surgeries by comparing the difference of VAS (visual analogue scale) scores between the two groups for 48 hours after surgery.Timepoint: To compare 4 in 1 block with modified 4 in 1 block using ultrasound for post-operative analgesia in cruciate ligament reconstruction in knee surgeries by comparing the difference of VAS (visual analogue scale) scores between the two groups for 48 hours after surgery.

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Secondary

Measure	Time frame
To note duration of postoperative analgesia using VAS in both groups up to 48hours after surgery. To note the site of pain, whether it is medial, lateral or upper side of knee To note the amount and type of rescue analgesia required. To note the extent of ambulation after 24 hours of surgery. To note the quadriceps muscle strength after 24 hours of surgery using the quadriceps strength test. To note the complications if any. To note patients overall experience score.Timepoint: The Quadriceps muscles strength will be tested at 24, 36 and 48 hour post operatively.	—

Measure

Time frame

To note duration of postoperative analgesia using VAS in both groups up to 48hours after surgery. To note the site of pain, whether it is medial, lateral or upper side of knee To note the amount and type of rescue analgesia required. To note the extent of ambulation after 24 hours of surgery. To note the quadriceps muscle strength after 24 hours of surgery using the quadriceps strength test. To note the complications if any. To note patients overall experience score.Timepoint: The Quadriceps muscles strength will be tested at 24, 36 and 48 hour post operatively.

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Countries

India

Contacts

Public ContactDr Divya Sagar

Pt BD Sharma PGIMS Rohtak

dr.priyankabansal1986@gmail.com8683921867

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026