Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: PSV-based Weaning: Patients are weaned from annaesthesia and extubated using machine delivered pressure support.
Intervention2: RBB-weaning and extubation: Patients are weaned and extub
Sponsors
All India Institute of Medical Sciences, Guwahati
Eligibility
Inclusion criteria
Inclusion criteria: ASA-PS I-III BMI 18.5 – 29.99 kg/m2 Both male and female Non-cardiac surgeries Elective surgeries
Exclusion criteria
Exclusion criteria: Obstetric patients Patients on vasoactive drug infusion for hypertensive crisis or shock Double lumen tube use Patients not extubated on table Anaesthesia duration less than 60 min and more than 300 min A special group of patients Any deviation or alternative technique of extubation if employed Patients requiring more than 3 units of PRBC transfusion Patients having eGFR less than 60 mL per min Known case of COPD GOLD class 3 and above Smoking 20 cigarettes per day in the past 48 hours
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Coughing and bucking severityTimepoint: Baseline, Extubation | — |
Secondary
| Measure | Time frame |
|---|---|
| haemodynamic variations like blood pressure, mean arterial pressure, heart rate, EtCO2, minute ventilationTimepoint: At 1, 3, 5, 7 and 10 min of reversal administration. And at 5, 10, 15, 20, 25 and 30 min of extubation | — |
Countries
India
Contacts
Public ContactDr Habib Md Reazaul Karim
All India Institute of Medical Sciences, Guwahati
Outcome results
None listed