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Comparing antiemetic efficacy of Inj propofol and Inj Ondansetron in laparoscopic surgeries under general anaesthesia

Comparison of Propofol vs Ondansetron for prevention of postoperative nausea and vomiting in laparoscopic Surgeries under general anaesthesia. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/07/070570
Enrollment
160
Registered
2024-07-14
Start date
Unknown
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Inj.Propofol intravenous: Group II will recieve intravenous propofol 0.5mg/kg,just before the removal of the last laparoscopic port before extubation Control Intervention1: Inj.Ondans

Sponsors

Shree Krishna Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)Patients scheduled for laparoscopic surgeries under general anaesthesia. 2)Patients who are able to provide informed and written consent. 3)Patients with ASA status I,II,III

Exclusion criteria

Exclusion criteria: 1)Who refuse to give written and informed consent. 2)Age less than 4 year old. 3)Haemodynamically unstable (patient in shock or on vasopressor support). 4)Induction agent other than propofol is used. 5)Positive history of drug allergy/allergy to study drugs. 6)Patient with middle ear infection and operated for middle ear problems 7)Patient on steroid therapy or opioid therapy, or medications causing nausea/vomiting 8)Pregnant and lactating patient. 9)Patient taking apomorphine . 10)Patients who had received antiemetic drugs within 24 h before anesthesia

Design outcomes

Primary

MeasureTime frame
To compare the incidence of nausea and vomiting postoperatively till 24 hours.Timepoint: Post operatively for 24 hours.

Secondary

MeasureTime frame
Time to extubation in both groups after giving antiemetics. Time & frequency when rescue antiemetic was given postoperatively till 24 hours. Type of analgesic & time at which it was given postoperatively till 24 hours. Timepoint: Na 2hr,6hr,12hr,24 hour 2hr,6hr,12hr,24 hour

Countries

India

Contacts

Public ContactDr.Shalini Singh

Pramukh Swami Medical College,Bhaikaka university

Birvank@charutarhealth.org9537122077

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026