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Comparison of levobupivacaine alone in one group and adding study drug clonidine with levobupivacaine in another group in patients undergoing laparoscopic gall bladder removal for pain relief after surgery

Comparative evaluation of intraperitoneal instillation of 0.25% levobupivacaine with or without clonidine for postoperative analgesia in patients undergoing laparoscopic cholecystectomy - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/07/070534
Enrollment
90
Registered
2024-07-12
Start date
Unknown
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K802- Calculus of gallbladder without cholecystitis

Interventions

Intervention1: Levobupivacaine with Clonidine: Intraperitoneal instillation of 28 ml of 0.25% levobupivacaine with clonidine 0.75 mcg/kg diluted up to 2 ml with normal saline a total volume of 30ml

Sponsors

Department of Anesthesia ESIC Medical College and Hospital Faridabad
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients of either sex, age 18 to 60 years and belonging to American Society of Anaesthesiologists (ASA) physical status I or II

Exclusion criteria

Exclusion criteria: Known allergy to study drugs Pregnant and lactating females Procedure converted to open cholecystectomy

Design outcomes

Primary

MeasureTime frame
To compare the duration of post-operative analgesia after intraperitoneal instillation of clonidine (0.75 mcg/kg) used as an adjunct to 0.25% levobupivacaine vs levobupivacaine alone in patients undergoing laparoscopic cholecystectomy in terms of duration of postoperative analgesiaTimepoint: At different time intervals during first 24 hours—

Secondary

MeasureTime frame
1) Total rescue analgesic consumption 2) Postoperative VAS score 3) Mean sedation score 4) Hemodynamic changes – MAP, HR Timepoint: At different time intervals during first 24 hours—

Countries

India

Contacts

Public ContactDr Saurav Sagar

ESIC Medical College and Hospital Faridabad

gogiaanoop@gmail.com9810318291

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026