Development of muscle strengthening device and its use in treatment of knee osteoarthritis.

Development of range driven motor unit recruitment device for functional re-education of intracaspsular muscles along with its clinical implication on osteoarthritic knee

Status

Recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/07/070498

Enrollment

Registered

2024-07-11

Start date

Unknown

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M170- Bilateral primary osteoarthritis of knee

Interventions

Intervention1: ROM-MURD (Testing): Phase-I: Subjects will be selected on the basis of inclusion criteria from Amritsar, Punjab, for the research. A complete explanation of the research will be given t

Eligibility

Inclusion criteria

Inclusion criteria: Phase I: Physically fit individuals who have an active lifestyle and do not engage in any form of muscle-strengthening exercises. Phase II: Patient having osteoarthritis of knee joint (Kellgren and Lawrence grade-2 or 3)

Exclusion criteria

Exclusion criteria: Phase I: -Individuals involved in strengthening exercise. -Histoy of knee injury/surgery. -Disease affecting the musculoskeletal system. Phase II: -Histoy of knee injury/surgery. -Knee joint deformity. -Disease affecting the musculoskeletal system. -Metal Senstivity. -Needle phobea. -Skin Infection. -Blood clotting disorder.

Design outcomes

Primary

Measure	Time frame
Phase I: -Electromyography (EMG) of Quadriceps and Hamstring muscles. -Isometric and Isokinetic strength analysis of the knee. -Functional near-infrared spectroscopy of the motor area of brain. Phase II: -Electromyography (EMG) of Quadriceps and Hamstring muscles. -Isometric and Isokinetic strength analysis of the knee. -Functional near-infrared spectroscopy of the motor area of brain. -Neumaric Pain Rating Score. -Pain pressure threshoild (Knee). -Gait Analysis -Western Ontario and McMaster Universities Arthritis Index (WOMAC) -Knee Injury and Osteoarthritis Outcome Score (KOOS) -Knee Outcome Survey Activities of Daily Living Scale (ADLS). -Patient Evaluation of Emotional Comfort Experienced (PEECE). -Copenhagen Knee ROM Scale -CT Scan of the knee (3D) -Ultasonography of muscles of knee joint.Timepoint: Pre-, during and post-intervention	—

Measure

Time frame

Phase I: -Electromyography (EMG) of Quadriceps and Hamstring muscles. -Isometric and Isokinetic strength analysis of the knee. -Functional near-infrared spectroscopy of the motor area of brain. Phase II: -Electromyography (EMG) of Quadriceps and Hamstring muscles. -Isometric and Isokinetic strength analysis of the knee. -Functional near-infrared spectroscopy of the motor area of brain. -Neumaric Pain Rating Score. -Pain pressure threshoild (Knee). -Gait Analysis -Western Ontario and McMaster Universities Arthritis Index (WOMAC) -Knee Injury and Osteoarthritis Outcome Score (KOOS) -Knee Outcome Survey Activities of Daily Living Scale (ADLS). -Patient Evaluation of Emotional Comfort Experienced (PEECE). -Copenhagen Knee ROM Scale -CT Scan of the knee (3D) -Ultasonography of muscles of knee joint.Timepoint: Pre-, during and post-intervention

—

Secondary

Measure	Time frame
NATimepoint: NA	—

Countries

India

Contacts

Public ContactDr Sarika

Guru Nanak Dev University

mks00004@gmail.com918860533343

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026