A study to compare local and systemic antibiotics on wisdom tooth surgery

A randomized controlled split mouth study of postoperative effects of locally delivered amoxicillin using platelet rich fibrin compared with preoperative systemic amoxicillin on impacted mandibular third molar surgery - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/07/070491

Enrollment

Registered

2024-07-11

Start date

Unknown

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K006- Disturbances in tooth eruption

Interventions

Intervention1: amoxicillin: 0.5ml of amoxicillin equivalent to 125mg mixed with prf single dose will be placed in extraction socket Control Intervention1: pre op 1 gram amoxicillin: 1 gram pre-antibio

Eligibility

Inclusion criteria

Inclusion criteria: subjects requiring surgical extraction of bilateral third molars subjects who have informed consent

Exclusion criteria

Exclusion criteria: subjects with infection around third molars subjects who are pregnant subjects with systemic disorders subjects who have allergy to amoxicillin subjects who have used antibiotics in past 2 weeks

Design outcomes

Primary

Measure	Time frame
Extraction Site Will Be Assessed For Pus Discharge And Mouth Opening.Timepoint: At 24 Hour, 72 Hour, 7th Day Post Operative Day.	—

Secondary

Measure	Time frame
Less side Effects Of Systemic AntibioticsTimepoint: 24 Hour, 72 hour, 7th Post Operativer Day	—

Countries

India

Contacts

Public ContactDr Nimsi

Manipal College of Dental Sciences

premalatha.shetty@manipal.edu9866697959

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026