A Survey Study On Participants Of Vyanga With Special Reference To Melasma And Randomized Comparative Trial With Intervention Of Mukhavyangaroga Nashaka Arka And Arjuna Twak Lepa

An Etiopathological Study Of Vyanga With Special Reference To Melasma And Randomized Comparative Trial Of Mukhavyangaroga Nashaka Arka And Arjuna Twak Lepa. - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/07/070469

Enrollment

100

Registered

2024-07-11

Start date

Unknown

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L819- Disorder of pigmentation, unspecified

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Subjects with Fitzpatrick skin types III, IV and V presenting with the classical signs and symptoms of Vyanga will be selected. Female subjects of childbearing potential using a reliable form of contraception during the course of the study excluding oral contraceptive pills at the time of the study or in the past 6 months (intrauterine device or condoms) or female of nonchildbearing potential (hysterectomy, bilateral ovariectomy or tubal section/ligation) Female subjects of childbearing potential with a negative urine pregnancy test before inclusion in the study Patient willing to follow up.

Exclusion criteria

Exclusion criteria: Pregnant women, nursing mothers Subjects having known chronic, contagious infectious disease, such as active tuberculosis, hepatitis B or C, HIV Subjects suffering from other pigmentation disorders Subject having used any cosmetic depigmenting agent within 2 weeks prior to inclusion Subjects who have used a topical or inhaled corticosteroid or systemic steroids within 1 month prior to inclusion in the study Subjects having used topical tretinoin within 3 months or topical hydroquinone within 6 months prior to inclusion Subjects with history of endocrinopathies Hyperpigmentation caused since birth like nevus of ota. Hyperpigmentation caused by tumor like malignant melanoma, Known case of any active skin malignancy Vyanga along with other Kushtha roga to be excluded.

Design outcomes

Primary

Measure	Time frame
Changes in mMASI –modified Melasma Area and Severity index in the patients of Vyanga (Melasma)Timepoint: Changes will be observed on day 0 and Day 60	—

Secondary

Measure	Time frame
changes in Physician’s Global Assessment scale and Melasma Quality of Life (MELASQOL)Timepoint: Changes will be observed on day 0 and Day 60	—

Countries

India

Contacts

Public ContactDr Surendra Kumar Sharma

National Institute of Ayurveda

ssurendr452@gmail.com9414361874

Outcome results