Health Condition 1: F40-F48- Anxiety, dissociative, stress-related, somatoform and other nonpsychotic mental disorders Health Condition 2: F10-F19- Mental and behavioral disorders due to psychoactive substance use Health Condition 3: F30-F39- Mood [affective] disorders Health Condition 4: F20-F29- Schizophrenia, schizotypal, delusional, and other non-mood psychotic disorders
Conditions
Interventions
Intervention1: Midazolam: 5mg,Intramuscular injection, given once and repeated once, if required.
Control Intervention1: Haloperidol plus Promethazine: 5mg haloperidol plus 50 mg promethazine ,Intramu
Sponsors
Government Medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Altered Mental Status Scale (AMSS) score greater than 1
Exclusion criteria
Exclusion criteria: Patient with known allergy of either midazolam or lorazepam or haloperidol or promethazine. Patient with medically reversible cause of agitation (hypotension, hypoxia or hypoglycemia). Patient known to be pregnant or lactating. Patient presenting with drug withdrawals or drug intoxication within past 48 hours. Patient with history of head injury within past 48 hours. Patient in active Delirium. Patient chemically restrained in past 24 hours.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time till adequate sedation using Altered Mental Status Scale (AMSS)Timepoint: 0 min, then every 3 minutes till adequate sedation | — |
Secondary
| Measure | Time frame |
|---|---|
| Need for repeat sedationTimepoint: 0,30 min, 1 hour, 6 hour, 12 hour | — |
Countries
India
Contacts
Public ContactLakhwinder Singh
Government Medical College and Hospital, Sector 32, Chandigarh
Outcome results
None listed