A Clinical trial to study the effect of two drugs, Ropivacaine and Bupivacaine in patient undergoing lower limb surgery

Clinical Evaluation of Efficacy and Safety of Hyperbaric Ropivacaine in Subarachnoid Block for Lower Limb Surgery: A Comparison with Hyperbaric Bupivacaine - Nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/07/070422

Enrollment

Registered

2024-07-10

Start date

Unknown

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: hyperbaric ropivacaine given for subarachnoid block in lower limb surgery: hyperbaric ropivacaine 22.5 mg drug volume 3 ml given Control Intervention1: hyperbaric bupivacaine given for

Eligibility

Inclusion criteria

Inclusion criteria: written and informed consent from patient patient undergoing any lower limb surgeries ASA grade I, II, III height more than 150 cm

Exclusion criteria

Exclusion criteria: patient refusal allergy to drugs local infection at the site of lumbar puncture uncontrolled systemic diseases patients having coagulopathy

Design outcomes

Primary

Measure	Time frame
compared the sensory and motor blockade characteristicsTimepoint: parameters measured at baseline, 2min, 4min, 6min, 8min, 10min,15min, 30min, 45min, 60min, 90min, 120min	—

Secondary

Measure	Time frame
compared hemodynamic parameters & observe complication in perioperative periodTimepoint: 24hours post operative	—

Countries

India

Contacts

Public ContactPatel Nitinkumar Ramanbhai

B.J. Medical College Ahmedabad

drseemagandhi@gmail.com9426373192

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026