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Comparison of dexmedetomidine and lidocaine infusion for postoperative analgesia in open cholecystectomy

Comparative evaluation of dexmedetomidine and lidocaine in postoperative analgesia in open cholecystectomy a double blind study

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/07/070420
Enrollment
80
Registered
2024-07-10
Start date
Unknown
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K802- Calculus of gallbladder without cholecystitis

Interventions

Intervention1: Perioperarive infusion of Dexmedetomidine in open cholecystectomy under general anaesthesia: Post operative pain (VAS score ) , haemodynamic parameters and requirements of rescue analg

Sponsors

Dr Kamal Jyoti Kashyap
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: age 20-60 years ,American Society of Anaesthesiologists (ASA) grade I and II , posted for open cholecystectomy under general anaesthesia.

Exclusion criteria

Exclusion criteria: Allergy to study drugs , obesity (BMI more than 35), renal failure , liver failure , pregnancy, alcohol abuse , chronic use of analgesic or other drugs , decreased autonomic control ,malampatti grade III and IV

Design outcomes

Primary

MeasureTime frame
Visual Analogue scale (VAS) scores at various time intervals, haemodynamic changesTimepoint: hemodynamic parameters will be assesd during intraoperative period and Visual Analogue scale (VAS score) , hemodynamic parameter and requirements of rescue analgesia will be assesd post operative period for 24 hours

Secondary

MeasureTime frame
Sedation score , time taken to achieve MPADSS ( Modified post anaesthestia discharge scoring system), time required for additional analgesia, measure requirements of rescue analgesia, total analgesic requirements in 24 hrsTimepoint: From end of surgery till 24 hours postoperative

Countries

India

Contacts

Public ContactDr Vivek Sabharwal

Government medical College Amritsar

gauryanheerak@yahoo.co.in9878883727

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026