Comparison of Tramadol, Ropivacaine, Lignocaine and Articaine in Patients undergoing Removal of Maxillary Posterior Tooth : To Compare Differences in Anesthetic action, Pain management, and Adverse effects

Comparative evaluation of 50mg Tramadol, 0.75 Percent Ropivacaine, 2 Percent Lignocaine and 4 Percent Articaine in Patients undergoing Extraction of Maxillary Posterior Tooth: Unveiling Differences in Anesthetic Action, Pain Management, and Adverse Effects – A Double Blinded Randomized Clinical Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/07/070401

Enrollment

220

Registered

2024-07-10

Start date

Unknown

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K029- Dental caries, unspecified

Interventions

Intervention1: 50mg Tramadol: Using 50mg Tramadol in Patients undergoing Extraction of Maxillary Posterior Tooth: Unveiling Differences in Anesthetic Action, Pain Management, and Adverse Effects Inter

Eligibility

Inclusion criteria

Inclusion criteria: 1-Patients both males and females aged 20–70 years. 2-Firm tooth requiring extraction. 3-Patients indicated for extraction of maxillary posterior tooth. 4-ASA -I and II physical status patients. 5-Patients willing to participate in the study.

Exclusion criteria

Exclusion criteria: 1-Pregnant or lactating females. 2-Patients with a history of drug allergy. 3-Patients presenting with any systemic diseases. 4-Patients with recent history of infection for which medications were taken. 5-Mobile tooth. 6-Tooth or root stumps with periapical lesions and abscesses. 7-RCT – Treated tooth requiring transalveolar extraction or with secondary infection. 8-Deleterious personal habits. 9-Patients not willing to participate in the study.

Design outcomes

Primary

Measure	Time frame
To assess the - Anesthetic action the onset of anesthesia and duration, The amount of anesthetic solution, Pain Management and Hemodynamic changesTimepoint: Time duration of anaesthetic action will be measured after giving local anesthesia till the end of extraction procedure. Pain management and Hemodynamic changes will be measured Pre operatively after 10 minutes giving local anesthesia. Intra operatively during the procedure. Post operatively after completion of tooth extraction till 10 minutes on the same day of extraction.	—

Measure

Time frame

To assess the - Anesthetic action the onset of anesthesia and duration, The amount of anesthetic solution, Pain Management and Hemodynamic changesTimepoint: Time duration of anaesthetic action will be measured after giving local anesthesia till the end of extraction procedure. Pain management and Hemodynamic changes will be measured Pre operatively after 10 minutes giving local anesthesia. Intra operatively during the procedure. Post operatively after completion of tooth extraction till 10 minutes on the same day of extraction.

—

Secondary

Measure	Time frame
To assess the adverse effects of local anesthetics.Timepoint: Time points are measured Pre operatively after 10 minutes giving local anesthesia. Intra operatively during the extraction procedure. Post operatively after completion of tooth extraction till 10 minutes on the same day of extraction.	—

Countries

India

Contacts

Public ContactDr G Gayathri

Thai Moogambigai Dental college and hospital Unit of DR. M.G.R Educational and Research institute

drgayathri20@gmail.com9841697444

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026