Health Condition 1: R69- Illness, unspecified
Conditions
Interventions
Intervention1: Patients of Group II to be transfused with PRBCs prepared from donors between 25 -45 years of age.: Patients of Group II to be transfused with PRBCs prepared from donors between 25 -45
Sponsors
Government Medical College and Hospital Chandigarh
Eligibility
Inclusion criteria
Inclusion criteria: Male blood donors in the age group of 18-65 years and meeting all other criteria for whole blood donation as per guidelines laid by Drug Controller General of India (DCGI). PRBCs less than 14 days old Patients admitted to multidisciplinary ICU Patients age more than 18 years Expected duration of ICU stay more than 48 hours APACHE II score between 10 – 20
Exclusion criteria
Exclusion criteria: Female blood donors , Blood donors where blood is collected in double or quadruple blood bags, Under collected/over collected bags, Blood donors reactive for any transfusion transmitted infections (TTI), Technical errors during component preparation, Cardiac diseases, Rare blood groups and Patients with pre-existing alloantibodies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MortalityTimepoint: 30 days | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Length of stay in hospital & ICU 2. Need for hemodynamic support 3. Need for mechanical ventilation 4. Adverse transfusion reaction 5. Clinically accepted measures of multiple organ dysfunction Timepoint: Every 7 days | — |
Countries
India
Contacts
Public ContactKshitija Mittal
Department of Transfusion Medicine, Government Medical College and Hospital, Chandigarh
Outcome results
None listed