Skip to content

Comparision of ketamine and magnesium sulfate nebulization to prevent sore throat after surgery in patients undergoing general anaesthesia.

A comparative evaluation of nebulized ketamine and nebulized magnesium sulfate for attenuating the post operative sore throat in patients undergoing surgery under general anaesthesia: A double blinded randomized clinical trial - NIL

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/07/070364
Enrollment
142
Registered
2024-07-10
Start date
Unknown
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Nebulization of 50mg Ketamine in 5ml normal saline in pre operative room: Study participants will be randomized into two groups. Intervention group receiving Nebulization of 50mg Ketami

Sponsors

Prem Kumar P
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients of either sex. 2. Patients of age group 18 to 65 years. 3. Patients of American Society of Anaesthesiologists (ASA) Physical grade I or II.

Exclusion criteria

Exclusion criteria: 1. Patients with history of post operative sore throat. 2. Patients with history of recent respiratory tract infection. 3. Patients with history of chronic obstructive pulmonary disease, asthma, head and neck surgery. 4. Patients with inserted nasogastric tube. 5. History of allergy to study drugs and recent NSAIDs medication and steroids. 6. Patient unwillingness/ refusal.

Design outcomes

Primary

MeasureTime frame
post operative sore throatTimepoint: Outcome will be assessed in post operative period at 0,2,4 hours

Secondary

MeasureTime frame
NILTimepoint: NIL

Countries

India

Contacts

Public ContactL Pradipkumar Singh

Regional Institute of Medical Sciences Imphal Manipur

drlaithangba@gmail.com7005238251

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026