A study to compare efficacy of excimer lamp with topical corticosteroids with topical corticosteroids alone in patients of vitiligo

A prospective clinical split-body study to determine the efficacy of excimer lamp 308nm with topical corticosteroids (clobetasol propionate 0.05 percentage)in patients of vitiligo compared with topical corticosteroids (clobetasol propionate 0.05 percentage ) alone - Nil

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/07/070317

Enrollment

Registered

2024-07-09

Start date

Unknown

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L80- Vitiligo

Interventions

Intervention1: Excimer lamp 308 nm: The vitiligo patches will be chosen for this treatment from both sides of body and face as the case may be. One side(e.g right side) will receive only the topical

Eligibility

Inclusion criteria

Inclusion criteria: Patients with more than 1 vitiligo patch and less than 10% BSA involvement Patients willing to come for treatment twice a week Age more than 6 years

Exclusion criteria

Exclusion criteria: Vitiligo affecting more than 10% BSA Not willing to follow up twice a week Patients not currently on any systemic therapy Patients not willing to give written informed consent Present or past history of photosensitivity or photodermatoses Patients with skin cancers or history of skin cancers or pre-malignant lesions Pregnant women and lactating mothers Active herpes infection

Design outcomes

Primary

Measure	Time frame
Vitiligo area severity index(VASI) will be calculated and compared for both sides of body i.e side which is treated with excimer lamp 308 nm with topical corticosteroids and topical corticosteroids alone at baseline and 12 weeks.The degree of repigmentation on both sides i.e. Excimer with topical therapy Vs topical therapy alone will be compared. Depigmentation on both sides will be calculated for this purpose, based on same technique as VASI Score- 10%, 25%, 50%, 75%, 90%, 100%.Timepoint: At Baseline and 12 weeks.	—

Measure

Time frame

Vitiligo area severity index(VASI) will be calculated and compared for both sides of body i.e side which is treated with excimer lamp 308 nm with topical corticosteroids and topical corticosteroids alone at baseline and 12 weeks.The degree of repigmentation on both sides i.e. Excimer with topical therapy Vs topical therapy alone will be compared. Depigmentation on both sides will be calculated for this purpose, based on same technique as VASI Score- 10%, 25%, 50%, 75%, 90%, 100%.Timepoint: At Baseline and 12 weeks.

—

Secondary

Measure	Time frame
NATimepoint: NA	—

Countries

India

Contacts

Public ContactChitra S Nayak

Topiwala National Medical College and BYL Nair Ch. Hospital

chitranayak054@gmail.com9029495590

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026