A Clinical trial to study the effect of Dadimadi gutika in the management of Primary Hypothyroidism.

A Randomised Controlled Clinical study to evaluate the efficacy of Dadimadi gutika in the management of Primary Hypothyroidism. - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/07/070307

Enrollment

Registered

2024-07-09

Start date

Unknown

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E038- Other specified hypothyroidism

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1) Signs and symptoms of primary hypothyroidism. 2) Newly diagnosed patient of primary hypothyroidism. 3) Subjects who are willing to give written informed consent. 4) Serum TSH level above 5.5µU/ml but below 20 µU/ml.

Exclusion criteria

Exclusion criteria: 1)Any complication arising during the treatment or if any patient discontinuing the treatment will be excluded. 2) Patients having active PR bleeding, active haemorrhoid, fissure in ano, fistula in ano etc. 3) Pregnant and lactating mothers 4) Hypertension, Diabetes Mellitus, Hypothyroidism due to excessive radiation therapy in treating cancer like lymphoma. 5) Malignancy of Thyroid Gland 6) Any other metabolic or systemic disease conditions where other treatment is urgent and was disturb the regimen. (HIV, Diabetes Cardiovascular disease, Tuberculosis etc.) 7) Patient having myxoedema coma. 8) Patients having X-Syndrome, Down’s syndrome, Turner’s syndrome, Klinefelter’s Syndrome carpel tunnel syndrome will be excluded. 9) Patient having Hypothyroidism due to Hypothalamic and Pituitary dysfunction. 10) Present history of any mental disorder. 11)Patient with chronic hyper acidity

Design outcomes

Primary

Measure	Time frame
1. To study the effect of ‘Dadimadi Gutika’ on Agnimandya (poor appetite), Shramashwasa (Dysnoea), Daurbalya (weakness), Khalitya (hairloss) etc. symptoms of primary hypothyroidism. 2. To study the effect of Dadimadi Gutika on serum TSH T3, T4 level. Timepoint: Clinically patients will be screened after every month for 3 months and TFT will be done before and after treatment.	—

Secondary

Measure	Time frame
1) To review the Ayurvedic & Modern literature on Primary Hypothyroidism. 2) To correlate Rasadhatvagnimandya, Rasapradoshajanya vyadhi & Primary Hypothyroidism. 3) To asses the possible mode of action of Dadimadi GutikaTimepoint: At 4th 8th & 12th week	—

Countries

India

Contacts

Public ContactDr Sunil Anandrao Bhaskare

R A Podar Govt (Ayu) College,Worli,Mumbai -18

bhaskaresunil14@gmail.com9819165638

Outcome results