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To find out the effect of antibiotics added to advanced platelet rich fibrin plus in the treatment of gum diseases.

Comparative clinical evaluation of adjunctive use of autologous advanced platelet rich fibrin plus, with and without 20 mg/ml doxycycline and 5mg/ml metronidazole, in the management of stage III and IV periodontitis patients A randomized placebo controlled clinical trial. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/07/070292
Enrollment
15
Registered
2024-07-09
Start date
Unknown
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Advanced PRF plus with and without antibiotics.: Advanced PRF plus (A-PRF+) will be prepared by obtaining 10 ml of patients blood from antecubital vein. This blood will be then transfer

Sponsors

Dr Hardik Raisoni
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: a.Patients within age group of 30-55 years. b. Participants maintaining good oral hygiene after completion of scaling and root planing. c.Stage III and IV periodontitis patients with at least four non-adjacent teeth with probing depth =5 mm.

Exclusion criteria

Exclusion criteria: a.Patients with chronic diseases such as diabetes mellitus, arthritis, thyroid disorder, etc. b.Patients using protective or orthodontic appliances c.Patients who are smokers or using any other tobacco products. d. Female patients who are pregnant and lactating. e Patients who are allergic to doxycycline and metronidazole

Design outcomes

Primary

MeasureTime frame
Pocket probing depthTimepoint: Pocket probing depth will be assessed at baseline(on the day of intervention), 1week, 4 weeks and 12 weeks—

Secondary

MeasureTime frame
Clinical attachment level Modified Papillary Bleeding Index Gingival IndexTimepoint: All Parameters will be assessed at baseline (on the day of intervention), 1week, 4 weeks and 12 weeks—

Countries

India

Contacts

Public ContactDrKunal S Sethi

MGVS KBH Dental College and Hospital

kunalks2001@yahoo.com9823020048

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026