Skip to content

Study will be done on patients coming for elective lower abdominal surgeries and effects of four different doses of dexmedetomidine with hyperbaric ropivacaine in spinal anaesthesia will be compared

Comparison of effects of different doses of dexmedetomidine as an intrathecal adjuvant to hyperbaric ropivacaine in lower abdominal surgeries : a prospective randomised controlled study - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/07/070283
Enrollment
100
Registered
2024-07-09
Start date
Unknown
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Four different doses of Dexmedetomidine ( 5 mcg, 10mcg, 15mcg,20mcg )as intrathecal adjuvant to hyperbaric ropivacaine in elective lower abdominal surgeries: Comparing the effects of fo

Sponsors

Simran Naval
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All ASA Grade 1 and 2, patients scheduled for elective lower abdominal surgery under subarachnoid block

Exclusion criteria

Exclusion criteria: Patients with hypertension, diabetes, spinal deformity, coagulation disorder, drug allergy, cardiovascular , respiratory or neurological disorders, pregnant patients, height less than 140cm, BMI more than 30kg per meter square, impaired liver and renal function tests, ASA Grade 3, 4, local skin infections

Design outcomes

Primary

MeasureTime frame
1.To asses onset and duration of sensory blockade from the time of drug adminitration 2. Maximum sensory level achieved and time taken for it 3.Time taken for 2 segment sensory regression 4. Onset and duration of motor blockade 5. Total duration of post op analgesiaTimepoint: 1.To asses onset and duration of sensory blockade from the time of administration of drug 2. Maximum sensory level achieved and time taken for it 3.Time taken for 2 segment sensory regression 4. Onset and duration of motor blockade 5. Total duration of post op analgesia every hour till time of rescue analgesia. Every outcome assessed every 30 seconds till 5 minutes, every 1 minuthe till next 10 minutes every 5 minutes till end of surgery

Secondary

MeasureTime frame
Changes in hemodynamic parameters and adverse effectsTimepoint: 24 hours after spinal anaesthsia

Countries

India

Contacts

Public ContactLakshmi Priya

Mysore Medical College And Research Institute

c7drpriya@gmail.com9845099554

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026