A clinical study comparing two routes for giving two classes of drugs by comparing postoperative quality of recovery using a 15 point questionnaire after cancer surgeries of abdomen under general anaesthesia.

Quality of Recovery (q0R 15) following administration of intravenous vs epidural opioids and non opioids in oncological abdominal surgeries under GA. - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/07/070242

Enrollment

Registered

2024-07-09

Start date

Unknown

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C179- Malignant neoplasm of small intestine, unspecified Health Condition 2: C55- Malignant neoplasm of uterus, partunspecified

Interventions

Intervention1: Epidural and Intravenous opioids and non opioids: To evaluate quality of recovery postoperatively after administration of IV fentanyl, IV paracetamol, Epidural Bupivacaine, Epidural bup

Eligibility

Inclusion criteria

Inclusion criteria: Known gastrointestinal or genitourinary cancer patients ASA grade III-IV Patients undergoing oncological abdominal surgeries under general anaesthesia

Exclusion criteria

Exclusion criteria: 1) Patient refusal 2) BMI = 30 kg/m 2 3) Clinically significant neurologic, psychiatric, CVS 4) Critically ill patient renal, respiratory and hepatic disease 5) Coagulation abnormalities 6) Local infection (for epidural) 7) Allergy to study drugs, pregnancy, drug abuse/ 8) Those who received analgesic, anxiolytic, antipschyciatric substance abuse medication within 6 hours before surgery 9) Redo surgery 10)Failure of extubation within 6 hours of surgery

Design outcomes

Primary

Measure	Time frame
Postoperative Quality of recovery using QoR 15 score Timepoint: 1 week	—

Secondary

Measure	Time frame
Immediate Aldrete score Return of bowel function in terms of peristalsis Time taken for first enteral feed Duration of hospital stay Incidence of drug related side effects Timepoint: Postoperative Quality of recovery using QoR 15 score every 24h till hospital stay.	—

Countries

India

Contacts

Public ContactArpita Thombre

Pt JNM Medical College, Raipur, C.G.

prati_jain@redifffmaail.com9827276620

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026