Effects of intravenous dexmedetomidine on spinal anesthesia in surgeries below umbilicus.

Effects of intravenous infusion of dexmedetomidine on spinal anesthesia with 0.5% hyperbaric levobupivacaine in infraumbilical surgeries. A prospective double-blind randomised controlled trial. - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/07/070219

Enrollment

Registered

2024-07-08

Start date

Unknown

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Group D: Group D received Dexmedetomidine infusion at 0.5microgram/kg/hour from 5 minutes before administering SAB till the end of surgery. Control Intervention1: Group S: Group S recei

Eligibility

Inclusion criteria

Inclusion criteria: Patients scheduled for infra umbilical surgeries of less than 2 hour duration. ASA physical status 1 and 2. Basal metabolic index of less than 30 kg per sq meters.

Exclusion criteria

Exclusion criteria: Patients with coagulopathy or hypovolemia. Pregnant patients. Obese patients. (BMI more than 30 kg per sq meters) Height of the patients more than 180 cm or less than 150 cm. Patients with significant cardiovascular system, pulmonary, hepatic, renal, neurological or psychological diseases. Recent use of any analgesics, sedative drugs or antidepressants. History of alcohol abuse. Any contraindications to SAB.

Design outcomes

Primary

Measure	Time frame
To compare the onset and duration of the analgesia with or without dexmedetomidine infusion in SAB by 0.5% hyperbaric levobupivacaine.Timepoint: The sensory blockade is assessed every minute until the T10-T12 dermatome level is achieved, then 5,10,15,20 and 30 minutes after intrathecal injection of Bupivacaine, then every 15 minutes thereafter.	—

Secondary

Measure	Time frame
Effect on motor blockade.Timepoint: The duration of motor blockade (DMB) will be assessed at 15 min intervals after the immediate end of surgery.;Incidence of hemodynamic changes.Timepoint: Hemodynamic changes evaluated by NIBP, HR monitoring intra-operatively and post operatively every 5 minutes.;Incidence of sedation.Timepoint: The level of sedation is evaluated intra- operatively and post-operatively every 15 min using Ramsey Level of Sedation Scale (RSS).	—

Measure

Time frame

Effect on motor blockade.Timepoint: The duration of motor blockade (DMB) will be assessed at 15 min intervals after the immediate end of surgery.;Incidence of hemodynamic changes.Timepoint: Hemodynamic changes evaluated by NIBP, HR monitoring intra-operatively and post operatively every 5 minutes.;Incidence of sedation.Timepoint: The level of sedation is evaluated intra- operatively and post-operatively every 15 min using Ramsey Level of Sedation Scale (RSS).

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Countries

India

Contacts

Public ContactRachana Kori

SDM College of Medical Sciences and Hospital, Dharwad.

Rachana.kori@gmail.com8277439222

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026