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Comparing Nerve Surgery and Nasal Steroids for Reducing Symptoms of Chronic Rhinitis: A Clinical Trial

Posterior nasal nerve neurectomy versus Intranasal Corticosteroids for Symptom Reduction in Chronic Rhinitis: Non Randomized Controlled Clinical Trial - PNNN

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/07/070201
Enrollment
70
Registered
2024-07-08
Start date
Unknown
Completion date
Unknown
Last updated
2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Posterior Nasal Nerve Neurectomy: The novelty of posterior nasal nerve neurectomy (PNNN) lies in its targeted approach to addressing chronic rhinitis by disrupting the neural pathways a

Sponsors

UPUMS Saifai
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: • Diagnosis of chronic rhinitis based on clinical assessment and TNSS. • No polyp or anatomical constraints on Computed tomography of paranasal sinuses. • Age between 18 and 65 years. • Willingness to participate and provide informed consent.

Exclusion criteria

Exclusion criteria: • Previous PNNN or any nasal surgery. • Known contraindications for corticosteroid treatment or PNNN. • Chronic rhinosinusitis with nasal polyposis. • Severe comorbidities or conditions affecting study outcomes.

Design outcomes

Primary

MeasureTime frame
Assessment of symptom severity- Total Nasal Symptom Score(TNSS), Visual Analog Scale(VAS); Quality of life improvement: Rhinoconjunctivitis Quality Of Life Questionnaire[RQLQ]Timepoint: 4 weeks, 12 weeks, 24 weeks and 1 year

Secondary

MeasureTime frame
Medication: usage of rescue medications (antihistamines, decongestants); Objective measures-as nasal endoscopy findings & peak nasal inspiratory flow ; Patient demographics & characteristicsTimepoint: 4 weeks, 12 weeks, 24 weeks, 1 year

Countries

India

Contacts

Public ContactDr Jitendra Chauhan

Uttar Pradesh University of Medical Sciences, Saifai

chauhanbhavya36@gmail.com9997634222

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026