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A study to compare the duration of pain relief with clonidine and morphine added to local anaesthetic drug Bupivacaine in spinal anaesthesia for patients undergoing vaginal hysterectomy.

Randomized, double blinded clinical trial to evaluate efficacy of intrathecal clonidine and intrathecal morphine as adjuvants to hyperbaric bupivacaine in spinal anaesthesia for patients undergoing vaginal hysterectomy. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/07/070200
Enrollment
140
Registered
2024-07-08
Start date
Unknown
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Clonidine: Dose - 0.1 micrograms per kilogram of body weight Route - Intrathecal Frequency - once before the start of surgery and will be observed for 24 hours Control Intervention1: Mo

Sponsors

Rajesh Ravi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: undergoing Vaginal hysterectomy under spinal anesthesia

Exclusion criteria

Exclusion criteria: Patients who have contraindications for regional anaesthesia will be excluded from the study

Design outcomes

Primary

MeasureTime frame
To compare the duration of postoperative analgesic effect of intrathecal clonidine and morphine when used as adjuvants to hyperbaric bupivacaine in spinal anaesthesiaTimepoint: 24 hours—

Secondary

MeasureTime frame
1. To compare postoperative pain scores in both groups. 2. To compare side effects like sedation, bradycardia, hypotension, urinary retention, nausea, vomiting, Itching, dry mouth and post operative shivering. 3. Time to regression of motor or sensory block 4. Time to first oral intake 5. Patient satisfaction scores Timepoint: 24 hours—

Countries

India

Contacts

Public ContactDr Anita Shirley

Christian Medical College

anjeyanth@gmail.com7358377164

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026