Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Propofol Infusion: During the conduct of motor evoked potential monitoring, anaesthesia is maintained by using propofol infusion in the first group
Control Intervention1: Ketofol Infusi
Sponsors
Sanjay Gandhi Post Graduate Institute of Medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: American Society of Anaesthesiologists Class I or II patients Adult Patients with BMI less than 30
Exclusion criteria
Exclusion criteria: Patients unable (legally incompetent) or unwilling to give consent. Previous history of psychiatric, anxiety or post-traumatic stress disorders. History of allergy to study drugs. Patient on sedative or hypnotic medication. Patients with chronic pain or on painkiller. Patients with severe hepatic or kidney disorders. Patients having a history of thyrotoxicosis or cardiac disorders. Patients on chronic beta blockers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Compare the effect of Propofol and Ketofol on amplitude and latency of Transcranial Motor Evoked Potentials when these agents are used with Fentanyl for the maintenance of general anaesthesia in cerebellopontine angle tumour surgeriesTimepoint: Amplitude and latency to be recorded every 30 minutes for the first 3 hours of surgery followed by every hour till the end of surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Comparison of hemodynamic intraoperative parameters between the two anaesthetic regimens every 30 minutes for the first 2 hours then every hour till the end of surgery. 2.Complications like nausea vomiting, pain at injection site, nystagmus, agitation, hallucinations etc Timepoint: 1. Every 30 minutes for the first 3 hours of surgery followed by hourly till the end of the surgery 2. After extubation of the patients which is usually 12 hours after surgery | — |
Countries
India
Contacts
Public ContactTwarita Singh
Sanjay Gandhi Post Graduate Institute of Medical Sciences
Outcome results
None listed