Study to compare post operative recovery time with propofol plus ketamine vs propofol plus Dexmedetomidine by target control infusion in patients undergoing laparoscopic cholecystectomy

A randomised clinical study to compare time to post-operative recovery using propofol with either ketamine or dexmedetomidine by target control infusion in patients undergoing laparoscopic cholecystectomy - nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/07/070090

Enrollment

Registered

2024-07-05

Start date

Unknown

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K80-K87- Disorders of gallbladder, biliary tract and pancreas

Interventions

Intervention1: compare time to post-operative recovery using propofol with either ketamine or dexmedetomidine by target control infusion in patients undergoing laparoscopic cholecystectomy : Patie

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients of either sex in the age group of 18-65 yrs. 2. ASA I and ASA II. 3. Patients undergoing laparoscopic cholecystectomy.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Comparison of mean/ median time taken to achieve Modified Aldrete score of =9. Timepoint: At the end of anaesthesia	—

Secondary

Measure	Time frame
• Mean/ median propofol consumed during surgery. • Proportion of patients with haemodynamic complications such as hypotension, hypertension, bradycardia, tachycardia. • Proportion of patients with irrelevant talk & hallucination. • Proportion of patients with postoperative nausea & vomiting. • Mean/ median post-operative analgesic requirement within 24 hours of surgery. • Proportion of patients with explicit recall Timepoint: 1 At the end of anaesthesia 2 Intra operative period 3 At the end of anaesthesia 4 At the end of anaesthesia 5 First 24 hrs of post operative period 6 First 24 hrs of post operative period	—

Measure

Time frame

• Mean/ median propofol consumed during surgery. • Proportion of patients with haemodynamic complications such as hypotension, hypertension, bradycardia, tachycardia. • Proportion of patients with irrelevant talk & hallucination. • Proportion of patients with postoperative nausea & vomiting. • Mean/ median post-operative analgesic requirement within 24 hours of surgery. • Proportion of patients with explicit recall Timepoint: 1 At the end of anaesthesia 2 Intra operative period 3 At the end of anaesthesia 4 At the end of anaesthesia 5 First 24 hrs of post operative period 6 First 24 hrs of post operative period

—

Countries

India

Contacts

Public ContactNishant kumar

Lady hardinge medical college

anshuguptabr@gmail.com9711000264

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026