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Comparison of inhaled ketamine-lignocaine vs nalbuphine-nignocaine on intubation conditions and heart/blood pressure responses while inserting a endotracheal tube while the patient is awake, using a flexible camera.

Comparison of Nebulized Ketamine-Lignocaine versus Nalbuphine-Lignocaine inhalation on intubating conditions and hemodynamic responses during Awake Fiberoptic Intubation - NIL

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/07/070076
Enrollment
64
Registered
2024-07-05
Start date
Unknown
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Nebulization with lignocaine with different adjuvants prior to fibreoptic intubation: Patients will be randomly allocated into two groups namely, group LN (1 ml of 0.1 mg/kg of nalbuphi

Sponsors

All India Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. American society of anaesthesiology grade I and II 2. Patients suspected to have difficult intubation requiring fibreoptic as an aid

Exclusion criteria

Exclusion criteria: 1.Pregnancy 2.Coagulopathy (Bleeding airway) 3.Cerebrovascular disease 4.systemic infection 5.Inability to understand the study protocol 6.Allergy to either of the drugs ketamine/nalbuphine/lignocaine 7.Psychopathy that may affect patient evaluation 8.Patient refusal 9.Pateints with significant renal, hepatic, pulmonary and neurological diseases 10.Pateints with history of drug abuse

Design outcomes

Primary

MeasureTime frame
To Compare the facial grimace scores, cough scores, sedation score between the groups To compare the hemodynamic parameters among the two groups Timepoint: 24hrs

Secondary

MeasureTime frame
To Compare Time taken for AFOI and Patient satisfaction scores in both the groupsTimepoint: 12 hours

Countries

India

Contacts

Public ContactDr. Surendra Kr Jangid

All India Institute of Medical Sciences

dr.skjangid@gmail.com8560919243

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026