Health Condition 1: E119- Type 2 diabetes mellitus without complications
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients who have not received any periodontal treatment in previous six months. 2. Patients diagnosed with T2DM as per American Diabetes Association criteria (2019). 3. Patients with a diagnosis of Generalized Periodontitis as per World Workshop Classification criteria (2017).
Exclusion criteria
Exclusion criteria: 1. Smokers and alcoholics. 2. Patients with systemic diseases like hypertension, cardiovascular diseases, rheumatoid arthritis, tumours, autoimmune diseases and renal diseases. 3. Pregnant, lactating females and post menopausal women. 4. Any other systemic disease which can alter the course of periodontal disease. 5. Patients on any medication like anti-inflammatory drugs, antibiotics and anti-epileptic drugs in the past 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparatively evaluate salivary and serum levels of Apelin and FGF-21 in periodontitis and T2DM patients. Explore any correlation of Apelin with FGF-21 and clinical parameters.Timepoint: Baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| Explore any correlation of Apelin with FGF-21 and clinical, biochemical & demographic parameters.Timepoint: Baseline | — |
Countries
India
Contacts
The Oxford Dental College