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Estimation of Apelin and Fibroblast growth factor-21 (FGF-21) in periodontal disease and Diabetes patients

Estimation of Apelin and Fibroblast growth factor 21 (FGF21) levels in saliva and serum in generalized periodontitis patients with and without Type 2 Diabetes mellitus (T2DM) - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/07/070058
Enrollment
80
Registered
2024-07-05
Start date
Unknown
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E119- Type 2 diabetes mellitus without complications

Interventions

Intervention1: NIL: NIL Control Intervention1: NIL: NIL

Sponsors

Dr Swathi S Kumar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients who have not received any periodontal treatment in previous six months. 2. Patients diagnosed with T2DM as per American Diabetes Association criteria (2019). 3. Patients with a diagnosis of Generalized Periodontitis as per World Workshop Classification criteria (2017).

Exclusion criteria

Exclusion criteria: 1. Smokers and alcoholics. 2. Patients with systemic diseases like hypertension, cardiovascular diseases, rheumatoid arthritis, tumours, autoimmune diseases and renal diseases. 3. Pregnant, lactating females and post menopausal women. 4. Any other systemic disease which can alter the course of periodontal disease. 5. Patients on any medication like anti-inflammatory drugs, antibiotics and anti-epileptic drugs in the past 6 months.

Design outcomes

Primary

MeasureTime frame
Comparatively evaluate salivary and serum levels of Apelin and FGF-21 in periodontitis and T2DM patients. Explore any correlation of Apelin with FGF-21 and clinical parameters.Timepoint: Baseline

Secondary

MeasureTime frame
Explore any correlation of Apelin with FGF-21 and clinical, biochemical & demographic parameters.Timepoint: Baseline

Countries

India

Contacts

Public ContactDr Swathi S Kumar

The Oxford Dental College

nichaniashish@hotmail.com9845252203

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026