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Prolongation of pain relief after injection of two drugs, dexamethasone and dexmedetomidine mixed with local anaesthetic above lamina of spine : a comparative study in patients of spine surgeries.

Comparison of analgesic efficacy of dexamethasone and dexmedetomidine as adjuvants to ropivacaine in ultrasound guided retrolaminar block for adult patients undergoing thoracolumbar spine surgery: a randomized controlled trial - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/07/070046
Enrollment
84
Registered
2024-07-05
Start date
Unknown
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Retrolaminar block with 0.2% ropivacaine with adjuvant dexamethasone: Retrolaminar block using plain 0.2% ropivacaine 20 ml and 4mg dexamethasone injected bilaterally at the level of ta

Sponsors

All India Institute of Medical Sciences Patna
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA physical status I and II patients undergoing thoracolumbar spinal surgeries less than or equal to five segments.

Exclusion criteria

Exclusion criteria: ASA III or more Allergy to the drugs Coagulopathy Infection at puncture site Mental disorder, Communication failure, unable to discriminate cutaneous pin prick. Chronic use of analgesics, inability to operate PCA pump Preexisting spinal cord disease prior lumbar spine surgery BMI more than or equal to 30

Design outcomes

Primary

MeasureTime frame
To compare the time to first rescue analgesic requirement in postoperative period. Timepoint: Within 24 hours of postoperative period

Secondary

MeasureTime frame
Severity of pain during postoperative period measured through NRS scaleTimepoint: 1,2, 4, 6, 12, 24 hours;To evaluate additional intraoperative fentanyl consumption in all groups.Timepoint: From administration of block till the end of surgery;Total postoperative fentanyl consumptionTimepoint: within 24 hours of postoperative period

Countries

India

Contacts

Public ContactDr Aakanksha Hiremath

AIIMS Patna

amarjeetdmch@gmail.com9570890646

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026