Skip to content

A clinical trial to compare the effect of two drugs Benzonatate and Levodropropizine in the treatment of chronic cough in ILD patients over a period of 4 weeks

An Open labelled Randomised Control Trial to compare the efficacy and safety of Benzonatate and Levodropropizine in the treatment of chronic refractory cough in ILD patients - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/07/070039
Enrollment
56
Registered
2024-07-05
Start date
Unknown
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J849- Interstitial pulmonary disease, unspecified

Interventions

Intervention1: TAB BENZONATATE 100 MG TDS COMPAIRED WITH SYP LEVODROPROPIZINE 10ML TDS: TAB BENZONATATE 100 MG TDS COMPAIRED WITH SYP LEVODROPROPIZINE FOR TREATMENT OF CHRONIC REFRACTORY COUGH IN ILD

Sponsors

Dr Naveen Dutt
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Age 18 year and older 2.Consenting to participate in the study 3.Radiologically or histopathologically diagnosed ILD 4.Those with chronic refractory cough 5.Patient taking same baseline treatment for ILD for last 2 weeks

Exclusion criteria

Exclusion criteria: 1.Cognitively impaired patient 2.Pregnant or lactating female 3.Not willing to participate in study 4.Severely ill patients 5.Known hypersensitivity to local anesthetic 6.Other treatable causes of cough 7. Active smoker 8.Already taking cough medications

Design outcomes

Primary

MeasureTime frame
Efficacy of Benzonatate and Levodropropizine in treatment of chronic refractory cough in ILD Patients using Leicester Cough QuestionnaireTimepoint: 2 Week and 4 week

Secondary

MeasureTime frame
1. To assess the efficacy of Benzonatate & Levodropropizine in symptomatic relief of chronic refractory cough in ILD Patients using cough VAS score. 2. To check the safety profile of Benzonatate & Levodropropizine therapy. 3. To identify the factors affecting the outcome of therapy Timepoint: 2 week & 4 week

Countries

India

Contacts

Public ContactDr Naveen Dutt

AIIMS Jodhpur

anmary322@gmail.com9044255400

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026