This study compares two drugs namely 0.5percent bupivacaine and 0.75 percent ropivacaine with an additive of dexmedetomidine used in transversus abdominis plane block for the duration of postoperative pain relief in patients undergoing lower abdominal surgeries under general anaesthesia

The effectiveness of 0.5 percent isobaric bupivacaine plus Dexmedetomidine Vs 0.75 percent ropivacaine plus dexmedetomidine for postoperative analgesia using ultrasound guided transversus abdominis plane block for abdominal surgeries under general anaesthesia : a randomised control study - NIL

Status

Active, not recruiting

Phases

Phase 3Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/07/070018

Enrollment

Registered

2024-07-04

Start date

Unknown

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G891- Acute pain, not elsewhere classified Health Condition 2: O- Medical and Surgical

Interventions

Control Intervention1: 0.5 percent Isobaric Bupivacaine and Dexmedetomidine: 15ml of 0.5 percent Bupivacaine-75mg and 10mcg of dexmedetomidine on each side for Transversus Abdominis Plane Block Contro

Eligibility

Inclusion criteria

Inclusion criteria: Patients between ages of 18 and 65 years, ASA grade 1 and 2 undergoing lower abdominal surgeries under General Anaesthesia

Exclusion criteria

Exclusion criteria: ASA grade 3 and 4 Hypersensitivity to Local anaesthesia patients with infection at the site of injection patients who have coagulopathies patients on systemic anticoagulant medications

Design outcomes

Primary

Measure	Time frame
Assessment of postoperative analgesia after Transversus Abdominis Plane block in patients undergoing abdominal surgeries using 0.5 percent bupivacaine and dexmedetomidine compared with 0.75 percent ropivacaine and dexmedetomidineTimepoint: 2 hours, 4 hours, 9 hours, 18 hours, 24 hours	—

Secondary

Measure	Time frame
Assessment of the effect of Transversus Abdominis Plane block on Perioperative hemodynamic status- Heart rate, Non-invasive Blood Pressure, SpO2Timepoint: 2 hours, 4 hours, 9 hours, 18 hours, 24 hours	—

Countries

India

Contacts

Public ContactDr MG Dhorigol

KLE DR Prabhakar Kore Hospital and MRC

mallappadhorigol@gmail.com9844778096

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026