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Comparing the Effectiveness of Two Bio-Ceramic Sealers in Treating Necrosed Teeth: A 6-Month Study Using CBCT-Advanced Imaging Technology

A comparative 6 months evaluation of clinical and radiographic outcome of necrotic single rooted teeth obturated using two different bioceramic sealers : A CBCT-based randomized clinical study - NIL

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/07/070005
Enrollment
48
Registered
2024-07-04
Start date
Unknown
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K041- Necrosis of pulp

Interventions

Intervention1: Angelus Bio-C Sealer: COMPOSITION: Tricalcium silicate, Dicalcium silicate, Tricalcium Aluminate, Calcium Oxide, Silicon Oxide, Zirconium Oxide, Polyethylene Glycol and Iron Oxide ROUTE

Sponsors

Dr Riddhi Vasa
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion criteria 1.Systemically healthy patients (Category: American Society of Anesthesiologists Class 2 or less than 2) 25 between 18 â?? 65 years of age. 2.Maxillary or mandibular single rooted teeth diagnosed with Pulpal necrosis with symptomatic or asymptomatic apical periodontitis with lesions that show periapical radiolucency with (CBCTPAI) Score 323 will be included in the study. 3.Re-treatment cases with periapical lesions with CBCTPAI Score 3 will be included in the study. 4.A written informed consent will be taken from all the patients and only those patients ready to sign the consent form will be included in the study.

Exclusion criteria

Exclusion criteria: Exclusion criteria 1.Pregnant and lactating women will be excluded. 2 Patients having teeth with poor prognosis, open apices, internal/external resorption, fractured Roots or visibly cracked tooth, grade 3 mobility, severe periodontal bone loss will be excluded from the study 3.Patients having teeth with complex root canal morphology such as Calcified canals, extreme curvatures or anomalies will be excluded from the study.

Design outcomes

Primary

MeasureTime frame
Healing of Periapical lesions is expected to be better than Cera seal bio-ceramic sealer in approximately 20 samplesTimepoint: Healing of periapical lesions will be assessed at baseline and after 6 months.

Secondary

MeasureTime frame
PERIAPICAL HEALING WILL BE ASSESED ON CBCT AT BASELINE AND AFTER 6 MONTHSTimepoint: At baseline & after 6 months interval.

Countries

India

Contacts

Public ContactDr Ajay Singh Rao

K.M. Shah dental college and hospital

drajayinendo@gmail.com8385017307

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Sep 19, 2026