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Effect of methotrexate on Thyroid function in Rheumatoid Arthritis Patients of Uttarakhand Region of India

Effect of methotrexate on Thyroid Profile in Rheumatoid Arthritis Patients at a Tertiary care Hospital of Uttarakhand Region of India: A Cross-Sectional Study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2024/07/069997
Enrollment
207
Registered
2024-07-04
Start date
Unknown
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M00-M99- Diseases of the musculoskeletal system and connective tissue

Interventions

Intervention1: nil: nil Control Intervention1: nil: nil

Sponsors

Dr Mahima Gupta
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All Patients of RA of age 18 years or more who are managed with methotrexate for = one year

Exclusion criteria

Exclusion criteria: Patient already having thyroid disease at the time of diagnosis of rheumatoid arthritis Pregnant patients Patient on drugs affecting thyroid function Patients undergone surgery or radiation around neck area Patient having any hypothalamo-pituitary disorder/disease Patients not willing to give consent.

Design outcomes

Primary

MeasureTime frame
To estimate the proportion of patients with altered thyroid profiles among the patients of Rheumatoid arthritis who were taking methotrexate for = 1 yearTimepoint: duration of study is 1 year

Secondary

MeasureTime frame
To evaluate the association of thyroid profile with different durations of methotrexate use. To evaluate the association of thyroid profile with different add on drugs in Rheumatoid arthritis management. To examine the Adverse Drug Reaction arising from anti-rheumatoid drug treatment Timepoint: duration of study is 1 year

Countries

India

Contacts

Public ContactDr Mahima Gupta

AIIMS Rishikesh

shazia.phar@aiimsrishikesh.edu.in9821425949

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026