Evaluation of patient acceptability and anti-plaque efficiency of neem chewing gum.

Evaluation and comparison of patient reported outcome measures and anti-plaque effectiveness of a novel herbal chewing gum containing neem extracts with placebo chewing gum: A double blind crossover clinical trial. - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/07/069955

Enrollment

Registered

2024-07-04

Start date

Unknown

Completion date

Unknown

Last updated

2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K051- Chronic gingivitis

Interventions

Intervention1: Herbal Chewing gum containing neem extracts: Herbal Chewing gum containing neem extracts will be prescribed to the patient and checked for anti-plaque activity for the first two days, f

Eligibility

Inclusion criteria

Inclusion criteria: Patients agreeing to comply with study protocol and instructions 2. Patients in good health in age range of 18-45 years. 3. Subject should have at least 20 natural permanent teeth in dentition 4. Periodontal pockets not greater than 3mm. 5. All subjects who are deemed medically fit. 6. Subjects having Gingival index score not more than 1.9. 7. Subjects who had a plaque index of greater than 2 at baseline.

Exclusion criteria

Exclusion criteria: Smokers and tobacco chewer 2. Patients with systemic diseases or compromising medical condition. 3. Patients on antibiotics one months prior to treatment. 4. Patients using orthodontic appliances either fixed or removable 5. Patients who have been using any mouth rinse containing chemical agents in previous 3 months. 6. Patients allergic or sensitive to any medication. 7. History of any surgical procedure in the selected area in the past six months. 8. Pregnant and lactating women, smokers, acute myocardial infarction within the past 6 months, use of pacemaker and uncontrolled metabolic diseases.

Design outcomes

Primary

Measure	Time frame
The anti-plaque effect assessed by plaque index after use of the novel herbal chewing gum containing neem extracts and the placebo chewing gum.Timepoint: The results will be assessed at baseline, 3rd day, 7th day, 10th day, 14th day, 17th day, 21st day of intervention	—

Secondary

Measure	Time frame
Any Adverse reaction or taste alteration after usage of chewing gum will be assessedTimepoint: These will be assessed at 3rd day, 6th day, 9th day	—

Countries

India

Contacts

Public ContactDr Pranjali Bawankar

Ranjeet Deshmukh Dental College and Research Center

Drpranjalibawankar@gmail.com09975128729

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026