Which is more effective Shuddha Guggulu or Shuddha Salai guggulu in patients of janugatasandhivata (knee osteoarthritis)

A Comparative Clinical Study to evaluate the efficacy of Shuddha Guggulu and Shuddha Salai guggulu in case of janugatasandhivata (w.s.r. to knee osteoarthritis) - NIL

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/07/069936

Enrollment

Registered

2024-07-04

Start date

Unknown

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M179- Osteoarthritis of knee, unspecified

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patient who give the consent to participate in study. 2. Patient of age group 41-70 years. 3. Patient fulfilling the diagnostic criteria as per clinical proforma. 4. The Patients who will be agree to stop all the previous medications of Osteoarthritis. - After diagnosis is established the patient will be included for clinical trial.

Exclusion criteria

Exclusion criteria: 1. Age below 41 years and above 70 years will be excluded. 2. Unwilling patient will be excluded. 3. Cases having severe joints deformities like Heberden node etc. will be excluded. 4. Cases with complications like severe ankylosed Joints and with infective joints disorders (Osteomyelitis), moderate to significant synovitis will also be excluded. 5. Pregnant women and Lactating mothers – will be excluded 6. Patient having Rheumatoid arthritis or having Gouty arthritis will be excluded. 7. Patient having secondary osteoarthritis (except control DM and thyroid disorder) infective or inflammatory arthritis of knee joint will be excluded.

Design outcomes

Primary

Measure	Time frame
v ?tapur?ad?tisparsa (Crepitus) sandhisula (Pain in or around the knee joint) pras ?ra? ?kuncanayoprav?ttiscasavedan ? (Painful flexion and extension of knee joint) hantisandhi (Restricted range of movement of knee joints) sandhi soth (Oedema)Timepoint: Before Trial, 15day, 30 day. 45 day, 60 day, 75 day, 90 day, after trial	—

Secondary

Measure	Time frame
Hb% CBC B.Sugar (Fasting-PP) E.S.R. R.A. factor S. Uric acid S. Calcium X- Ray Knee joints – AP/ Lateral view Timepoint: Before Trial and after trial;Tenderness of knee joints Morning stiffness (Less than half an hour) Sandhi soth (Synovial effusion) Increased walking time Timepoint: Before Trial, 15day, 30 day. 45 day, 60 day, 75 day, 90 day, after trial;X-ray of the affected joints areas showinG 1. Osteophytes (Bony swelling) 2. Reduced joint space 3. Subchondral bone sclerosis 4. Osteoporosis 5. Bone fragilityTimepoint: Before Trial, 15day, 30 day. 45 day, 60 day, 75 day, 90 day, after trial	—

Measure

Time frame

Hb% CBC B.Sugar (Fasting-PP) E.S.R. R.A. factor S. Uric acid S. Calcium X- Ray Knee joints – AP/ Lateral view Timepoint: Before Trial and after trial;Tenderness of knee joints Morning stiffness (Less than half an hour) Sandhi soth (Synovial effusion) Increased walking time Timepoint: Before Trial, 15day, 30 day. 45 day, 60 day, 75 day, 90 day, after trial;X-ray of the affected joints areas showinG 1. Osteophytes (Bony swelling) 2. Reduced joint space 3. Subchondral bone sclerosis 4. Osteoporosis 5. Bone fragilityTimepoint: Before Trial, 15day, 30 day. 45 day, 60 day, 75 day, 90 day, after trial

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Countries

India

Contacts

Public ContactMohd Waseem

State Ayurvedic College and Hospital Lucknow

sharadjohri47@gmail.com9454032188

Outcome results