Health Condition 1: K004- Disturbances in tooth formation
Conditions
Interventions
Intervention1: Concentrated Growth Factor (CGF): CGF wiLL be used as scaffold
Preparation of CGF:
â?¢ Two disposable 10 ml non-anticoagulant tubes and a centrifuge will be used.
â?¢ 10ml of intravenou
accelerated for 30 seconds
centrifuged at
2700 rpm for 2 min, 2400 rpm for 4 min, 2700 rpm for 4 min, and 3000 rpm for 3
min
and decelerated for 36 secs to stop.
â?¢ At the end of the automated pre-programmed cycle, the centrifuge tube will
encompassa concoction of four different layers
the uppermost or the 1stlayer
contained serum, the 2ndlayer was composed of a fibrin buffy coat, the 3rdlayer
constituted the much needed growth factors, and lastly, the lowermost or the 4thlayer
was
Sponsors
ICMR
Eligibility
Inclusion criteria
Inclusion criteria: Children with non-vital immature permanent teeth requiring endodontic treatment ASA I and II Patient Compliant Patient and Parent
Exclusion criteria
Exclusion criteria: Post/core required for final restoration Patient Allergic to any medicaments or antibiotics to be used during the procedure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical outcomes Resolution of signs and symptoms like pain, swelling, pus drainage, tooth mobility Tooth survival Restoration of function 2. Radiographic outcomes Resolution of periapical pathologyTimepoint: Time intervals At Baseline 1 Month Post Procedure 3 Months Post Procedure 6 Months Post Procedure 1 year Post Procedure | — |
Secondary
| Measure | Time frame |
|---|---|
| 1 Clinical outcomes Positive response to pulp vitality tests 2. Radiographic outcomes Thickening of the dentinal walls of the root canals Continuation of root development Closure of the root apexTimepoint: Time intervals At Baseline 1 Month Post Procedure 3 Months Post Procedure 6 Months Post Procedure 1 year Post Procedure | — |
Countries
India
Contacts
Public ContactAditya Saxena
ITS Dental College Hospital and Research Centre
Outcome results
None listed