Comparative analysis of intrathecal hyperbaric ropivacaine o.75% with fentanyl versus hyperbaric bupivacaine 0.5% with fentanyl in elective lower abdominal surgery

Comparision of efficacy of intrathecal hyperbaric(0.75%) Ropivacaine with fentanyl and hyperbaric (0.5%) Bppivacaine with fentanyl in elective lower abdominal surgeries-A prospective randomised double blind clinical study - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/07/069884

Enrollment

128

Registered

2024-07-04

Start date

Unknown

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: O- Medical and Surgical Health Condition 3: 8- Other Procedures Health Condition 4: 8- Other Procedures Health Condition 5: 8- Other Procedures

Interventions

Intervention1: Hyperbaric Ropivacaine (0.75%)3ml with fentanyl0.5 ml given for subarachanoid block: Hyperbaric Ropivacaine 22.5 mg(3 ml) and fentanyl 25 mcg(0.5 ml) Total 3.5 ml volume of drug will be

Eligibility

Inclusion criteria

Inclusion criteria: ASA1/2 Elective lower abdominal surgery (Hernioplasty,Herniorraphy,hydrocele repair,Appendecectomy,perineal surgery) Duration of surgery 1.5 to 2 hours

Exclusion criteria

Exclusion criteria: Patient refusal Patient with uncontrolled systemic disease , psychiatric illness,local site infection ,allergic to local anesthetic and adjuvant,spine deformity,previous spine surgery ,height less than 140 cm,BMI more than 30 kg/m2, pregnant women

Design outcomes

Primary

Measure	Time frame
Onset of sensory block at L1 dermatome level ,time to achive maximum sensory level,Time for two segment regression,Total duration of sensory block Onset of motor blockade,Time to achieve complete motor blockade, maximum motor blockade,Total duration of motor blockadeTimepoint: Every 15 sec for 2 minutes and then every minute for 10 minute after completion of intrathecal injection and then every 30 minute during surgery	—

Measure

Time frame

Onset of sensory block at L1 dermatome level ,time to achive maximum sensory level,Time for two segment regression,Total duration of sensory block Onset of motor blockade,Time to achieve complete motor blockade, maximum motor blockade,Total duration of motor blockadeTimepoint: Every 15 sec for 2 minutes and then every minute for 10 minute after completion of intrathecal injection and then every 30 minute during surgery

—

Secondary

Measure	Time frame
Any changes in hemodynamic parameters loke pulse rate,blood pressure,spo2 perioperatively Time to first micturation, Time for mobilisationTimepoint: 1 min 3 min 5 min 10 min 20 min 30 min 60 min 90 min 120 min	—

Countries

India

Contacts

Public ContactBhuriya Mittal Himabhai

Government Medical College Vadodara

dr.kashmira13@gmail.com9099045151

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026