Health Condition 1: M056- Rheumatoid arthritis with involvement of other organs and systems Health Condition 2: M321- Systemic lupus erythematosus withorgan or system involvement
Conditions
Interventions
Intervention1: Telmisartan + standard of care (Tadalafil with cold protective measures): Once the diagnosis of either SLE OR Rheumatoid arthirits with Raynauds Phenomena is made 10 patients will be g
Sponsors
Institute of Medical Sciences Banaras Hindu University Varanasi Uttar Pradesh 221005
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age greater than or equal to 18 years. 2. Patients diagnosed as Systemic Lupus Erythematosus and Rheumatoid Arthritis with history of Raynaud’s Phenomenon. 3. Willing to give signed written consent.
Exclusion criteria
Exclusion criteria: 1.Any co-existing significant/incapacitating chronic illness 2.Patient with symptomatic CAD 3.Patients on oral or sublingual nitrates 4.Patient who are pregnant or reproductive couples who have intention of pregnancy 5.Patients with known contraindication to either of IPs or SOC
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement in severity and frequency of Raynauds Phenomenon after introduction of drug with standard of careTimepoint: 0,6 and 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Any untoward effect or hypersensitivityTimepoint: At 1 and 2 weeks | — |
Countries
India
Contacts
Public ContactRajat Singh
Institute of Medical Sciences
Outcome results
None listed