Effect of melatonin ( a hormone for sleep induction) supplement on the quality of sleep and control of blood pressure in hemodialysis patients

Study of Oral Melatonin on Sleep quality and Blood pressure in Maintenance Hemodialysis patients - NIL

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2024/07/069863

Enrollment

Registered

2024-07-03

Start date

Unknown

Completion date

Unknown

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N186- End stage renal disease

Interventions

Intervention1: Oral melatonin supplementation: Oral melatonin supplementation 3 mg dosage once daily at bedtime for a study period of 3 months to maintenance hemodialysis patients with sleep dist

Eligibility

Inclusion criteria

Inclusion criteria: 1.Maintenance hemodialysis patients who are more than 18 years 2. Dialysis vintage more than one year 3. Baseline Pittsburgh Sleep Quality Index more than 5

Exclusion criteria

Exclusion criteria: Less than 18 years, more than 65 years, with advanced liver disease, malignancy, heart failure, active infection, pregnancy, BMI more than 40, psychosis, patient on hypnotics

Design outcomes

Primary

Measure	Time frame
Effect of oral melatonin on sleep quality, 24 hour ambulatory BP and depression scoring in maintenance hemodialysis patientsTimepoint: 3 months after oral melatonin supplementation	—

Secondary

Measure	Time frame
Effect of oral melatonin on depression scoringTimepoint: 3 months supplementation	—

Countries

India

Contacts

Public ContactSakthirajan R

Madras Medical College

draatral@gmail.com9444126080

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026