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A Study to evaluate the effect of local application of Tulsi plant derived ointment comparing it with numbing gel Lidocaine in the management of mouth ulcers.

A Comparative study to assess the efficacy of topical Tulsi (Ocimum sanctum) and topical Lidocaine in the management of recurrent aphthous stomatitis (minor). - NIL

Status
Recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2024/07/069828
Enrollment
48
Registered
2024-07-02
Start date
Unknown
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K120- Recurrent oral aphthae

Interventions

Intervention1: topical Tulsi: Subjects are prescribed with 10g of topical Tulsi and instructed to applied at the site of ulcer 4times/day,using cotton buds to form a thin smear over the ulcer, for a d

Sponsors

Anu M
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Subjects giving a history of recurrent aphthous stomatitis-minor(ulcers that measure less then 10 mm, and heal within 4 to 14 days without scarring) with a minimum of two episodes in a year. Subjects with 1to 3 minor recurrent aphthous ulcers of less than 48 hours duration.

Exclusion criteria

Exclusion criteria: Subjects with any systemic disorders. Subjects with the habit of smoking or alcoholism. Subjects undergoing orthodontic therapy. Subjects who had undergone tooth extraction or any dental surgical procedure in the past 2 weeks. Pregnant and lactating women.

Design outcomes

Primary

MeasureTime frame
Reduction in size of the ulcer, intensity of pain and degree of erythema Timepoint: Day 1,4 and 7 of using topical Tulsi and topical Lidocaine

Secondary

MeasureTime frame
Reduction in recurrences of the ulcerTimepoint: Day 30 and 60

Countries

India

Contacts

Public ContactAnu M

Best Dental Science College

sudarshanr093@gmail.com9444498736

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026