Health Condition 1: F102- Alcohol dependence
Conditions
Interventions
Intervention1: Tablet Quetiapine 25mg BD: Tb. Quetiapine will be initiated at a dose of 25 mg BD along with standard therapy- Symptom Triggered Benzodiazepine regimen till resolution of symptoms.
Tab
Sponsors
Dr Jeel Vasa
Eligibility
Inclusion criteria
Inclusion criteria: Age between 18 to 60 years Patients of either gender Patients with alcohol dependance suffering alcohol withdrawal in delirium (ICD 10 criteria F10.4)
Exclusion criteria
Exclusion criteria: Ages less than 18 years, or more than 60 years. Patients with comorbid intellectual disability, history of psychosis, dementia Patients with symptoms of Wernicke’s encephalopathy showing ophthalmoplegia, ataxia on clinical examination Patients with a QTc interval above 500 msecs Patient with recent (less than 3 months) cardiac events Patients with prior allergic reactions to Quetiapine Patients with a history of extrapyramidal symptoms with use of Quetiapine. Patients with suspected multifactorial causes for the onset of delirium
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Resolution of delirium tremensTimepoint: Every 6 hours scales will be applied to check if delirium has resolved | — |
Secondary
| Measure | Time frame |
|---|---|
| Length of hospital stayTimepoint: End of 10 days & every day thereafter;Number of SOS medications needed throughout admissionTimepoint: At the end of 10 days & every day thereafter | — |
Countries
India
Contacts
Public ContactDr Jeel Vasa
All India Institute of Medical Sciences Nagpur
Outcome results
None listed