Health Condition 1: F322- Major depressive disorder, singleepisode, severe without psychotic features
Conditions
Interventions
Intervention1: T.ESCITALOPRAM AND C.GUTBRAX: T.ESCITALOPRAM
Dose 10mg
Frequency one tablet daily in the morning
Route of administration is per oral
Total duration is 10 weeks
C.GUTBRAX
Dose 23 Billi
Sponsors
SVS Medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients who have been diagnosed as moderate or severe depressive disorder according to ICD 10 first episode or multiple episodes. 2.Subjects willing to give consent.
Exclusion criteria
Exclusion criteria: 1. Patients diagnosed with Mild Depressive Disorder. 2. Patients diagnosed with Bipolar Depression. 3. Patients with a Pre-existing mental illness other than Depressive disorder. 4. Patients who are diagnosed with Thyroid abnormalities. 5. Patients who were diagnosed with Gastrointestinal infections or with inflammatory bowel disease during 4 weeks before inclusion into the study. 6. Patients who have been on Steroids or Antibiotics during 4 weeks before inclusion into the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Decrease in the Hamilton depression rating score (HAM -D 21) is taken as response to the cap.GUTBRAX.Timepoint: Hamilton depression rating score assessment is done on day of recruitment into study then after 2 weeks ,6 weeks and 10 weeks. | — |
Secondary
| Measure | Time frame |
|---|---|
| Assess the tolerability of the C.GUTBRAX.Timepoint: Assessing the tolerabilty after 2 weeks of initiation of treatment then after 6 weeks and 10 weeks. | — |
Countries
India
Contacts
Public ContactDr K ASHOK REDDY
SVS Medical College and Hospital
Outcome results
None listed